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A leading comprehensive brain tumor program, using molecular diagnostic, gene expression analysis,
cutting edge clinical trials and advanced medical informatics to customize treatment plans for cancer patients.
 Latest Headlines
•Celldex Loses a Partner in Brain Tumor Treatment
Fri, 03 Sep 2010 18:35:36 -0700
•Pfizer Ends Celldex Accord for Brain-Tumor Vaccine; Celldex Shares Plunge
Fri, 03 Sep 2010 07:08:10 -0700
•Celldex, Pfizer Split Over Brain Tumor Drug
Fri, 03 Sep 2010 05:13:27 -0700
•Gigantic Community Yard Sale to Benefit Young Man
Sun, 05 Sep 2010 14:12:45 -0700
•Celldex plummets after Pfizer ends vaccine pact
Sat, 04 Sep 2010 02:33:26 -0700
•Update: Elsa's Angels help 10-year-old with brain tumor
Fri, 03 Sep 2010 08:20:42 -0700
•Celldex Plunges After Pfizer Ends Cancer Vaccine Pact
Fri, 03 Sep 2010 07:27:24 -0700
•Remembering George Smith as 'a man and a movement'
Sun, 05 Sep 2010 10:32:11 -0700
•GO! Outoors for Sept. 5-11
Sat, 04 Sep 2010 22:35:03 -0700
•Brain tumor teaches man patience
Tue, 31 Aug 2010 00:13:33 -0700

* Headlines are from industry sponsored news wires, medical journals and established news organizations from around the world . Please consider the source of the content when viewing the story.
   
 
Improving clinical outcomes in glioblastoma brain tumors with genetic analysis

In this study, featured in the New England Journal of Medicine, glioblastomas patients who were treated with gefitinib or erlotinib, were found to be responsive to EGFR kinase inhibitors and strongly associated with coexpression by the tumor of EGFRvIII and PTEN.



UCLA Neuro-Oncology & SiliconMED Launch Online Tool Correlating Gene Expression Levels with Overall Survival of Brain Cancer Patients

Genomic analysis is a powerful new tool permitting unprecedented insights into how brain tumors form and has been enabled primarily through microarray technology. ProbeSetAnalyzer.com, a new web based tool, is aiming to help clinicians and researchers take the massive amount of data created by microarrays and better visualize gene expression levels and how they relate to the overall survival of brain cancer patients.

Most Popular
.  Clinical Trials
.  Probe Set Analyzer
.  Our Team
.  Brain Tumor Translational Resource
.  Art of the Brain
.  Personalized Medicine using Targeted Molecular Therapy
.  Online Giving
.  How our Glioblastoma Multiforme Patients Perform

Spring / Summer 2010
Breakthroughs



Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach.
Phys Med Biol.
55(12):3271-85.

mTOR signaling in glioblastoma: lessons learned from bench to bedside.
Neuro-Onc


Kinetics of 3'-deoxy-3'-18F-fluorothymidine during treatment monitoring of recurrent high-grade glioma.
J Nucl Med.
51(5):720-7.

Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group.
J Clin Oncol
28(11):1963-72.

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
Proc Natl Acad Sci U S A.
107(14):6459-64

All Information content hearof is designed for educational purposes only and is not for the purpose of rendering medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. Any specific questions you may have regarding an individual's medical condition should be directed to the individual's primary care physician or other attending physician. In addition, if you have or suspect you may have a health problem, you should consult your health care provider.

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Copyright © 2010 UCLA Neuro-Oncology Program | Timothly Cloughesy MD; Director
All Rights Reserved.

[Content Published:9/5/2010 3:11:23 PM PST]