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A leading comprehensive brain tumor program, using molecular diagnostic, gene expression analysis,
cutting edge clinical trials and advanced medical informatics to customize treatment plans for cancer patients.
 Latest Headlines
•Action Report: 6-year-old boy battling brain tumor separated from his grandmother
Thu, 29 Jul 2010 20:49:35 -0700
•WBTV's Improving the Odds special
Thu, 29 Jul 2010 16:38:08 -0700
•Penguins PA announcer John Barbero dies at age 65
Tue, 27 Jul 2010 08:06:53 -0700
•VIDEO: Local veterans groups make one man's dream a reality
Thu, 29 Jul 2010 08:35:49 -0700
•Penguins PA announcer Barbero dies at 65
Tue, 27 Jul 2010 16:10:38 -0700
•Brain tumor enhances artist's vision
Sun, 25 Jul 2010 02:21:21 -0700
•Master support group listing
Thu, 29 Jul 2010 21:00:00 -0700
•Remembering George Smith as 'a man and a movement'
Fri, 30 Jul 2010 00:06:42 -0700
•Bearing the worst with the best
Wed, 28 Jul 2010 16:08:50 -0700
•Pittsburgh Penguins public address announcer John Barbero dies
Tue, 27 Jul 2010 08:32:40 -0700

* Headlines are from industry sponsored news wires, medical journals and established news organizations from around the world . Please consider the source of the content when viewing the story.
   
 
Improving clinical outcomes in glioblastoma brain tumors with genetic analysis

In this study, featured in the New England Journal of Medicine, glioblastomas patients who were treated with gefitinib or erlotinib, were found to be responsive to EGFR kinase inhibitors and strongly associated with coexpression by the tumor of EGFRvIII and PTEN.



UCLA Neuro-Oncology & SiliconMED Launch Online Tool Correlating Gene Expression Levels with Overall Survival of Brain Cancer Patients

Genomic analysis is a powerful new tool permitting unprecedented insights into how brain tumors form and has been enabled primarily through microarray technology. ProbeSetAnalyzer.com, a new web based tool, is aiming to help clinicians and researchers take the massive amount of data created by microarrays and better visualize gene expression levels and how they relate to the overall survival of brain cancer patients.

Most Popular
.  Clinical Trials
.  Probe Set Analyzer
.  Our Team
.  Brain Tumor Translational Resource
.  Art of the Brain
.  Personalized Medicine using Targeted Molecular Therapy
.  Online Giving
.  How our Glioblastoma Multiforme Patients Perform

Spring / Summer 2010
Breakthroughs



Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach.
Phys Med Biol.
55(12):3271-85.

mTOR signaling in glioblastoma: lessons learned from bench to bedside.
Neuro-Onc


Kinetics of 3'-deoxy-3'-18F-fluorothymidine during treatment monitoring of recurrent high-grade glioma.
J Nucl Med.
51(5):720-7.

Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group.
J Clin Oncol
28(11):1963-72.

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
Proc Natl Acad Sci U S A.
107(14):6459-64

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Copyright © 2010 UCLA Neuro-Oncology Program | Timothly Cloughesy MD; Director
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[Content Published:7/30/2010 1:32:28 AM PST]